21 Question AQ-Test for Alzheimer's & MCI
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AQ is a simple test for people worried about memory and cognition. Using just 21 questions, the Alzheimer's Questionnaire boasts 90% accuracy in distinguishing between normal aging, MCI and dementia. Learn how it works or take an online version here.
It can be difficult to distinguish between people with normal age-associated memory loss and those with mild cognitive impairment (MCI). However people with MCI are at a greater risk of developing Alzheimer's disease (AD), and identification of these people would mean that they could begin treatment as early as possible. New research published in BioMed Central's open access journal BMC Geriatrics shows that specific questions, included as part of a questionnaire designed to help diagnose AD, are also able to discriminate between normal memory loss and MCI. The questionnaire is called the "Alzheimer's Questionnaire" (AQ). Click here to take the 21-question AQ (Online Alzheimer's Questionnaire).
Loss of memory can be distressing for the person affected and their families and both the patient and people who know them may complain about their memory as well as difficulties in their daily lives. However memory problems can be a part of normal aging and not necessarily an indicator of incipient dementia.
A pilot study had indicated that a simple, short, questionnaire (AQ), designed to identify people with AD by using informant-reported symptoms, was also able to recognize people with MCI.
The AQ consists of 21 yes/no questions designed to be answered by a relative or carer in a primary care setting.
While validating the AQ, researchers from Banner Sun Health Research Institute discovered that four of the questions were strong indicators of aMCI (aMCI is Amnestic Mild Cognitive Impairment, a subtype of Mild Cognitive Impairment where memory loss is the predominant symptom.)
Six of these questions are known to be predictive of Alzheimer's and are given an extra weighting of 2 points. This results in a possible total score of 21 + 6 = 27.
A score above 15 was indicative of Alzheimer's disease. A score between 5 and 14 indicated the possibility of the milder condition known as aMCI. Scores of 4 or lower indicate that the person does not have significant memory problems.
|
What the total score means: |
|
|
0 to 4 |
No cause for concern |
|
5 to 14 |
Warning sign of possible MCI |
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15 or |
Warning sign of possible dementia such as Alzheimer’s |
The questions fall into five categories:
- Memory
- Orientation
- Functional ability
- Visuospatial ability
- Language.
Psychometrist Michael Malek-Ahmadi, who led the study, explained, "People with aMCI were more often reported as repeating questions and statements, having trouble knowing the date or time, having difficulties managing their finances and a decreased sense of direction." He continued,
"While the AQ cannot be used as a definitive guide to diagnosing AD or aMCI, it is a quick and simple-to-use indicator that may help physicians determine which individuals should be referred for more extensive testing."
Click here to take the 21-question AQ
(Online Alzheimer's Questionnaire).
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More Information
- BMC Genomics is an open access, peer-reviewed journal that considers articles on all aspects of genome-scale analysis, functional genomics, and proteomics.
- BioMed Central (http://www.bannerhealth.com/) is an STM (Science, Technology and Medicine) publisher which has pioneered the open access publishing model. All peer-reviewed research articles published by BioMed Central are made immediately and freely accessible online, and are licensed to allow redistribution and reuse. BioMed Central is part of Springer Science+Business Media, a leading global publisher in the STM sector.
- For 24 years, Sun Health Research Institute, part of nonprofit Banner Health, has been a leader nationally and internationally in the effort to find answers to disorders of aging including Alzheimer's disease, Parkinson's disease. The institute, together with its Arizona Alzheimer's Consortium partners, has been designated by the National Institutes of Health as one of just 29 Alzheimer's Disease Centers in the nation. The institute's Cleo Roberts Center for Clinical Research takes laboratory discoveries to clinical trials that foster hope for new treatments. Banner Health is Arizona's leading health care provider and second largest private employer. For more information, visit http://www.BannerSHRI.com.
Source:
Informant-reported cognitive symptoms that predict amnestic mild cognitive impairment. Michael Malek-Ahmadi, Kathryn Davis, Christine Belden, Sandra Jacobson and Marwan N Sabbagh. BMC Geriatrics
.
