Research News

FDA-Approved Bexarotene Improves Memory, Reversing Alzheimer's in Mice

3D-Scan of Brain with Alzheimer's

VIDEO & ARTICLE

Researchers discover that an approved anti-skin-cancer drug rapidly clears the amyloid plaque from the brain that is largely held responsible for Alzheimer's. Find out how it reverses cognitive defects and improves memory.

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18F Sees Alzheimer's

Scan using 18F-labeled tracer FDDNP

Alzheimer's, watch out! Doctors can finally see their target. Using PET scans, 18F-labeled tracers allow doctors to see Alzheimer's brain plaques and fight them. Learn why 4 companies are racing for FDA approval to deliver the tracers to labs, clinics and hospitals.

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Investment into Tau Research Grows

Alzheimer's Panel Discussion at BigThink.com

VIDEO + TRANSCRIPT

BigThink.com asks, "Why is it so hard these days to get a grant from NIA around beta amyloid when you can get it for tau?" 

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How Far We Have Come in Alzheimer's Research

Video for Research News

VIDEO

As recently as 30 years ago, scientists typically diagnosed  Alzheimer's as senility. They thought it was a normal part of aging. Hear leading Alzheimer's disease researchers describe how far the field has come since Dr. Alois Alzheimer discovered the disease more than a century ago. (HBO Re-run)

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If Alzheimer’s Spreads, Can We Kill It Like a Virus?

brain

VIDEO & ARTICLE

For decades, researchers debated whether Alzheimer’s starts in independent brain regions or spreads from one place to connected areas. New evidence shows that it spreads. Learn how this opens fresh opportunities for Alzheimer's therapies.

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Memory Gate Opened by Deep Brain Stimulation

Video for Research News

VIDEO & ARTICLE

UCLA researchers successfully stimulated a junction in the brain that holds potential for improving recall in dementia patients. Learn about this “golden gate” to memory called the “entorhinal cortex.”

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Contrasting Colors & Larger Type Enhance Thinking in Dementia

Bingo Card

Discover why boosting contrast and enlarging letters can help people with dementia move around safely, eat better and think more clearly.

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PBT2 Dementia Trial is 2012 Editor's Choice

Copper, Iron & Zinc cubes

PBT2 finished 2011 taking 4 giant steps forward. First, it delivered shining results in a new study. Also, The Alzheimer's Discovery Foundation and Quintiles backed it with fresh funding. Next, it launched a big trial. Finally, Japan awarded it patents for Alzheimer's and Huntington's diseases. Find out more facts making PBT2 2012's most promising drug trial.

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Protein Folding Protection Prevents Alzheimer's & Huntington's

Video for Research News

VIDEO & ARTICLE

To do its job properly in brain cells, a protein first must fold itself into the proper shape. If it doesn’t, Alzheimer's, Parkinson's or Huntington's disease may result. Two studies from Northwestern University offer strategies for tackling protein misfolding.

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Can Wine's Resveratrol Slow Huntington's Disease Via SIRT1 Gene?

A man drinking a glass of wine

Red wine's resveratrol is an easily-available anti-aging supplement. Studies indicate it activates the SIRT1 gene. Read how SIRT1 appears to dramatically delay and slow Huntington’s disease.

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Highly Promising Gammagard Advances into Phase III

Bottle of Gammagard

Gammagard Liquid Infusion is ranked by Alzheimer’s Weekly as one of the top 5 most promising treatments in the fight against Alzheimer's. The latest clinical trial brings Gammagard to an advanced testing stage. Learn about its progress and promise.

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Leukine Rushed to Clinical Trials

"A box of Leukine (generic: sargramostim)."

VIDEO & ARTICLE

An impressive study suggests Leukine should be tested in humans as a potential treatment for Alzheimer's disease. It is already FDA approved to treat cancer and has a strong safety record.

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How Quickly Does Alzheimer's Progress?

Doctor filling out a chart

In Alzheimer's, memory and cognition decline at different rates for different people. What are the ranges and probabilities? Are we getting better at answering the question on an individual basis?

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MCI Does NOT Mean Pre-Alzheimer's

Senior businessman contemplating his memory's health

MCI (Mild Cognitive Impairment) is a common label for early memory problems. Doctors thought Alzheimer's or other dementias inevitably followed. Learn how this half-truth was shattered by a ground-breaking British study.

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Green Fluorescent Protein Shows Folate Inhibits Alzheimer's

Yeast species

Folate fights Alzheimer's, according to Australian government researchers. They used a green fluorescent protein from jellyfish to check for Alzheimer's inhibitors. Their success in identifying folate may be the tip-of-the-iceberg in the discovery of effective compounds to combat dementia..

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