
Diranersen Hits Setback, Yet Marks Turning Point in Alzheimer’s Treatment
A Different Kind of Alzheimer’s Drug Just Delivered One of the Most Interesting Results in Years

A Different Kind of Alzheimer’s Drug Just Delivered One of the Most Interesting Results in Years

“It is exciting to see efficacy of potential new drugs for Dementia with Lewy Bodies, the most common dementia after Alzheimer’s. It is a huge area of unmet need,” said Dr. Marwan Sabbagh.

A twice-daily pill called ALZ-801 brings new hope to high-genetic-risk Alzheimer’s. Early findings suggest meaningful slowing of decline, stronger safety, and brain structure protection.

Trontinemab, an experimental drug developed by Roche, has sparked excitement in large trials for slowing Alzheimer’s faster and safer than anything before.

VIDEO + ARTICLE: A promising new oral therapy for Alzheimer’s is now recruiting participants across the USA and Australia, offering fresh hope to families affected by this devastating condition.

The big Alzheimer’s culprits are Amyloid and Tau. Biogen made Leqembi to treat amyloid. Now, they are betting on BIIB080 to treat tau. Learn how this exciting new treatment just got FDA Fast Track Designation.

Participants in a new study had inherited genetic variants that lead to early-onset Alzheimer’s. Among those who received the drug the longest – an average of eight years – the treatment lowered the risk of developing symptoms from essentially 100% to about 50%.

WashU Medicine-led trial evaluating investigational drug from Eli Lilly and Company aims to stop disease before symptoms arise

Learn about 2025’s newly approved or potential Alzheimer’s drugs. These include Leqembi, Kisunla, Remternetug, Semaglutide, Trontinemab and Bepranemab.

New Alzheimer’s drugs clear brain plaque made of amyloid-beta. 9 years ago, researchers discovered another Alzheimer’s culprit called amyloid-ETA. Now, they’ve possibly figured out how it works. Learn how balancing these two suspects may hold the key to success in current clinical trials.

VIDEO + TRANSCRIPT: Cocoa’s flavanol phytonutrients, without sugar & fat, improve arterial function. They fight strokes and atherosclerosis, triggers of vascular dementia. So, is chocolate healthy? See Dr. Gregger tease out the research.

DIAGNOSIS VIDEO + ARTICLE:
Country music legend Kris Kristofferson Alzheimer’s misdiagnosis ruined his career. Turned out he had Lyme disease. Learn about his remarkable recovery and the signs to look for.

VIDEO + ARTICLE: People who get more REM sleep get less dementia. REM sleep is when dreaming occurs. Learn about the stages of sleep and their dementia links.

An intriguing study of 120 grandmothers might surprise you. Doctors know socially engaged people have better cognition and less dementia. But can a person get too much of a good thing? What’s the right balance?

Enjoy this great duet between a musician with dementia and his son. A triumph of spirit over Alzheimer’s! Sing-a-long if you like!

It looks like a sneeze cannot give anyone Alzheimer’s. While Alzheimer’s abnormal disease proteins do spread from cell-to-cell, they are not “infectious”. Check out the facts.

TEEPA CARE VIDEO: Learn about Alzheimer’s 6 stages. Teepa Snow shows what to expect, while keeping the focus on the person for whom you care.
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