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Alzheimer's And Dementia Weekly

Support & Insight for the Autumn of Life

Sundowning

How To Care for Sundowning

June 27, 2025 12 Comments

“Sundowning” describes agitation and anxiety often felt towards the end of the day in dementia. See what it is and what you can do about it.

Sundowning, Daylight Savings Time and Dementia

November 3, 2024 No Comments

Daylight Savings Time can disrupt the environment and daily routine of people with Alzheimer’s. See how to be proactive when changing the clock.

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Memory Boosted by Intermittent Fasting in Alzheimer’s Lab

June 5, 2024 No Comments

A groundbreaking study corrected the circadian disruptions seen in Alzheimer’s mice by using time-restricted feeding. This may improve sleep, sundowning, confusion and memory.

The Three E’s of Managing Sundowning

May 6, 2024 1 Comment

Environment, Empathy and Engagement improve sundowning, or sundowners syndrome, in dementia and Alzheimer’s. Explore effective strategies to comfort and support your loved ones symptoms.

What Causes Sundowning? Frustration or Chemistry?

January 7, 2024 10 Comments

In “SUNDOWNING SYNDROME,” people with dementia show high levels of anxiety, agitation, overactivity and delirium. It typically occurs in late afternoon and evening, before their normal time to go to bed. Learn how brain biology explains “sundowning.”

5 Tips to Ease Sundowning in Dementia

October 25, 2023 7 Comments

VIDEO ON SUNDOWNING: See UCLA’s Dementia Care Program deal with end-of-day agitation and irritability, known as “Sundowning”. A caregiver asks, “My loved one’s behavior tends to get worse when the sun starts to go down. He appears exhausted and restless. What can I do to get him through this time of the day?”

Enhanced Light Sensitivity Contributes to “Sundowning” in Alzheimer’s

August 11, 2023 1 Comment

Alzheimer’s research from UVA Health suggests that enhanced light sensitivity may contribute to “sundowning” – the worsening of symptoms late in the day.

Sundowning Care from Sunset ’til Sunrise

July 30, 2023 No Comments

For 12 years, a special program called “Dusk ‘Til Dawn” has been successfully fighting sundowning.

FDA Okays Rexulti for Agitation in Alzheimer’s

June 5, 2023 No Comments

The US Food and Drug Administration has announced the supplemental approval of Rexulti (brexpiprazole) oral tablets for the treatment of agitation associated with dementia due to Alzheimer’s. Learn more.

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FDA Votes 9-1 to Advance Rexulti for Alzheimer’s

May 15, 2023 No Comments

The FDA has approved the supplemental New Drug Application (sNDA) of REXULTI® (brexpiprazole) for the treatment of agitation associated with Alzheimer’s. It’s the first such treatment to be approved in the US. Learn more.

Insulin Nasal Spray for Alzheimer's Drug

Insulin Nasal Spray Reaches the Alzheimer’s Brain

July 24, 2025

Could a nasal spray help memory loss? A new study using Aptar’s delivery system shows insulin reaching key brain regions, offering new hope for treating Alzheimer’s and mild cognitive impairment.

Xanamem for Alzheimer’s Trial: A Single Pill Once a Day

July 23, 2025

VIDEO + ARTICLE: A promising new oral therapy for Alzheimer’s is now recruiting participants across the USA and Australia, offering fresh hope to families affected by this devastating condition.

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“Is Leqembi Worth It?” Costs and the Road to Wider Access

July 22, 2025

Leqembi, the first Alzheimer’s-modifying drug, is a giant step forward—but how many people are getting it, and what does it really cost the average American? We dig into the numbers, the barriers, and the path forward.

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A Grandchild for One Day Keeps Dementia Away

An intriguing study of 120 grandmothers might surprise you. Doctors know socially engaged people have better cognition and less dementia. But can a person get too much of a good thing? What’s the right balance?