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Alzheimer's And Dementia Weekly

Support & Insight for the Autumn of Life

Sundowning

How To Care for Sundowning

June 27, 2025 12 Comments

“Sundowning” describes agitation and anxiety often felt towards the end of the day in dementia. See what it is and what you can do about it.

Sundowning, Daylight Savings Time and Dementia

November 3, 2024 No Comments

Daylight Savings Time can disrupt the environment and daily routine of people with Alzheimer’s. See how to be proactive when changing the clock.

Woman in Pink Long Sleeves Eating Dinner Alone

Memory Boosted by Intermittent Fasting in Alzheimer’s Lab

June 5, 2024 No Comments

A groundbreaking study corrected the circadian disruptions seen in Alzheimer’s mice by using time-restricted feeding. This may improve sleep, sundowning, confusion and memory.

The Three E’s of Managing Sundowning

May 6, 2024 1 Comment

Environment, Empathy and Engagement improve sundowning, or sundowners syndrome, in dementia and Alzheimer’s. Explore effective strategies to comfort and support your loved ones symptoms.

What Causes Sundowning? Frustration or Chemistry?

January 7, 2024 10 Comments

In “SUNDOWNING SYNDROME,” people with dementia show high levels of anxiety, agitation, overactivity and delirium. It typically occurs in late afternoon and evening, before their normal time to go to bed. Learn how brain biology explains “sundowning.”

5 Tips to Ease Sundowning in Dementia

October 25, 2023 7 Comments

VIDEO ON SUNDOWNING: See UCLA’s Dementia Care Program deal with end-of-day agitation and irritability, known as “Sundowning”. A caregiver asks, “My loved one’s behavior tends to get worse when the sun starts to go down. He appears exhausted and restless. What can I do to get him through this time of the day?”

Enhanced Light Sensitivity Contributes to “Sundowning” in Alzheimer’s

August 11, 2023 1 Comment

Alzheimer’s research from UVA Health suggests that enhanced light sensitivity may contribute to “sundowning” – the worsening of symptoms late in the day.

Sundowning Care from Sunset ’til Sunrise

July 30, 2023 No Comments

For 12 years, a special program called “Dusk ‘Til Dawn” has been successfully fighting sundowning.

FDA Okays Rexulti for Agitation in Alzheimer’s

June 5, 2023 No Comments

The US Food and Drug Administration has announced the supplemental approval of Rexulti (brexpiprazole) oral tablets for the treatment of agitation associated with dementia due to Alzheimer’s. Learn more.

woman wearing yellow and pink floral dress wahing carrots

FDA Votes 9-1 to Advance Rexulti for Alzheimer’s

May 15, 2023 No Comments

The FDA has approved the supplemental New Drug Application (sNDA) of REXULTI® (brexpiprazole) for the treatment of agitation associated with Alzheimer’s. It’s the first such treatment to be approved in the US. Learn more.

Calm Asian female wearing white pajama sleeping in comfortable bed with white sheets near modern mobile phone in morning

Sleep Clears Brain Waste, Lowers Dementia Risk

July 4, 2025

Berkeley researchers reveal deep sleep might protect memory—even in the face of Alzheimer’s. Could your nightly rest be the brain’s best defense?

Brain cells (neurons) where two substances are highlighted: tau, appears in red, and glycogen appears in green. Where the two overlap, the color turns yellow or orange.

Brain Sugar Breakthrough: Can Fasting and Fat Burners Shield Your Mind?

July 2, 2025

A new Buck Institute discovery reveals neurons process sugar in a surprising way— and unlocking this “brain sugar” pathway could lead to powerful Alzheimer’s treatments.

A peaceful sleeping infant wrapped in a soft, warm blanket on a cozy white surface.

Do Babies’ Tau Proteins Hold the Key to Curing Alzheimer’s?

July 1, 2025

Why Do Babies Have More Alzheimer’s Protein Than Adults? A Surprising Clue to Future Treatments

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