One Weight-Loss Drug Slowed Alzheimer’s, Two Didn’t. That’s Good News.
Three major GLP-1 trials came out in late 2025. One weight-loss drug slowed early Alzheimer’s decline, while two others failed. Surprisingly, this mixed pattern may point the way toward a promising new treatment direction.
Good News for Valiltramiprosate for Alzheimer's (ALZ-801)
A twice-daily pill called ALZ-801 brings new hope to high-genetic-risk Alzheimer’s. Early findings suggest meaningful slowing of decline, stronger safety, and brain structure protection.
8 Care Tips to Boost Holiday Joy
DEMENTIA & HOLIDAY PLANS: Relatives with dementia may be frail or have special emotional, mental and physical health needs. Check out these ways to help them enjoy the holiday season.
Lecanemab Can Delay Alzheimer’s 8 Years: New Data, New Hope
New long-term data suggests lecanemab could delay the shift from mild memory loss to moderate Alzheimer’s by up to eight years—offering families precious time and renewed hope.
Your Social Frailty Index: A New Way to Delay Dementia
Strengthening social connections may offer a surprising boost to long-term brain health.
Shingles Vaccine Rollout Surprisingly Reduces Dementia
New research hints at a simple, widely available vaccine that may help protect brain health.
8 Care Tips to Boost Holiday Joy
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DEMENTIA & HOLIDAY PLANS: Relatives with dementia may be frail or have special emotional, mental and physical health needs. Check out these ways to help them enjoy the holiday season.
Lecanemab Can Delay Alzheimer’s 8 Years: New Data, New Hope
New long-term data suggests lecanemab could delay the shift from mild memory loss to moderate Alzheimer’s by up to eight years—offering families precious time and renewed hope.
Welcome.
For almost 20 years, Alzheimer’s & Dementia Weekly has highlighted only the most essential articles, studies, tools, and videos, from the overwhelming river of dementia-related information. Google gets new posts on Alzheimer’s or dementia every 7 minutes.
For anyone seeking clarity or support, that constant flow can be exhausting and discouraging.
Alzheimer’s Weekly filters, translates, and explains what matters most, helping hundreds of thousands of families, clinicians, and care teams around the world make sense of the latest research and best practices.
This site is dedicated to everyone who works—often quietly and tirelessly—to preserve dignity in the community of people living with dementia. (Learn more about us.)
What is it?
Diagnosis
Quality of Life
Living Well with Dementia
What Does Living with Alzheimer’s Feel Like?
Few movies and books capture the Alzheimer’s experience like Dr. Lisa Genova’s “Still Alice.” See Lisa describe how “Still Alice” is helping families stay connected while living with Alzheimer’s.
I May Be Forgetful
This pleasant poem highlights how people living with dementia may be feeling.
Designing Homes for Extra Care
The Housing Learning and Improvement Network looks at the design process and philosophy behind creating a successful Extra Care scheme.
The Dangers of Driving with Alzheimer’s
VIDEO + CHECKLIST OF 15 WARNING SIGNS: Memory problems caused by Alzheimer’s make driving unsafe. See how. Watch this thought-provoking video to open up the discussion with family members, friends and patients.
BRAIN HEALTH
Diet
And Prevention
Choline, Nuts & Dementia: What New Studies Really Say
December 1, 2025
New research suggests choline—a nutrient linked to memory and cognitive resilience—may help people with Alzheimer’s and at high dementia risk. Here’s why nuts, a heart-healthy and cholesterol-free food, can play a powerful role in daily dementia care.
Arginine on the Frontline: New Hope for Alzheimer’s
November 23, 2025
A new study suggests a simple nutrient — arginine — may reduce amyloid-β buildup in Alzheimer’s. The findings, from animal studies, raise an encouraging question: could arginine eventually play a role in Alzheimer’s prevention? Here’s what the research shows — and what caregivers should know.
6 Brain-Boosting Foods + 3 Smart Nutrition Habits to Reduce Alzheimer’s Impact
November 20, 2025
A growing body of research shows that what we eat can make a real difference in how the brain ages. Discover the everyday foods that strengthen memory, support cognition, and help reduce the impact of Alzheimer’s — starting with simple choices you can make today.
Library of Posts
Progressing to a Cure
Research
Shingles Vaccine Rollout Surprisingly Reduces Dementia
New research hints at a simple, widely available vaccine that may help protect brain health.
Good News for Valiltramiprosate for Alzheimer’s (ALZ-801)
A twice-daily pill called ALZ-801 brings new hope to high-genetic-risk Alzheimer’s. Early findings suggest meaningful slowing of decline, stronger safety, and brain structure protection.
Bill Gates Discusses Alzheimer’s Research on CBS Sunday Morning
In this web exclusive, Microsoft co-founder and philanthropist Bill Gates talks with CBS News chief medical correspondent Dr. Jon LaPook about research into Alzheimer’s, a disease which affected his own father.
Magnesium’s Importance to Brain Health
DIET: MAGNESIUM appears to do a lot to maintain brain health, prevent cognitive impairment (CI), and fight Alzheimer’s. Learn how.
Unpacking Ways to Help Dementia
Treatments & Therapies
Tips, Insights & Helpful Guides
Caregiving
Shopping
7 Best Clocks for Dementia
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In dementia, people repeatedly ask, “What’s the time?” “What day is it?” Easily solve this with Dementia-clocks / Calendar-clocks. Check out 7 clocks with good looks and limitless patience.
AI Phone-Friend Eases Loneliness of Alzheimer’s & Dementia
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A simple voice-based AI companion is offering gentle conversation and emotional support for people living with Alzheimer’s and dementia — no apps, no screens, and no tech skills required.
Make a Dementia-Friendly House
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HOME IMPROVEMENT & DEMENTIA – VIDEO:
See simple changes that create a more dementia-friendly environment at home. Get ideas to help you give people living with dementia the best quality of life, emotional well-being and independence.
Caregivers Delight: 31-Day Pill Organizer, 4 Times a Day
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PRODUCT OF THE WEEK: Caregivers love this pill box, as do patients and professionals. Simply fill it once a month. Roomy, simple, ingenious.
Best Digital Photo Frames for Dementia
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Looking for the best digital photo frame for a loved one with dementia? Many frames claim to be senior-friendly. We explore the Pix-Star series, rated best for its combination of features and value for the money.
Bookshop
5 Communication Tips for Dementia Caregivers
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TALKING TO PEOPLE WITH DEMENTIA IS VITAL when getting together. Check out 5 handy communication tips and books.
Don’t Walk Away from Alzheimer’s
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There is a choice we make when a loved one gets Alzheimer’s. Walk away, or don’t walk away. Marilyn’s Mom told her to walk away. Marilyn chose not to. She’s glad she didn’t. Share her journey.
The Original Picture Puzzle
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BOOK OF THE WEEK: The Editors of Brain Games for Adults put together this book of original picture puzzles. The variety of brain teasers make this a perfect gift for people living with dementia.
Explaining Alzheimer’s to Young Children: A Compassionate Guide
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Explaining Alzheimer’s to young children can be a daunting task. Here are 10 easy suggestions for explaining Alzheimer’s to young children.
Avie J. Rainwater, III, Ph.D., ABPP, FAACP
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Clinical Psychology / Neuropsychology
LIFECARE PSYCHOLOGY GROUP, LLC
Love & Compassion
Experience 12 Minutes in Alzheimer's
Just what is a loved one with dementia going through? This virtual Alzheimer’s tour reveals more than you ever imagined.
Songs
But I’ll Tell You All About Her
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Sharing the story of a person with Alzheimer’s, when their own memory fails, can be a true act of dignity and love. Ryan Nealon sings of the significance of “Telling You All About Her.”
I Promise You Forever, You Will Never Leave My Mind
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“Damn this old dementia, for robbing me of time, But I promise you forever, you will never leave my mind.”
OKLAHOMA! Belted Out by Dad with Dementia & Son
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Here’s Teddy Mac and his son Simon singing Oklahoma – one of his showstoppers – from a few years ago.
Inspiring & Uplifting
Film & Music
A Big Thanksgiving Laugh from A Little Old Lady
November 26, 2025
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FUNNY VIDEO – HAPPY THANKSGIVING: Mary Maxwell, a diminutive “little old lady,” shines a very funny light on the foibles of aging, to the delight of an audience filled with senior-care experts.
Listening and Playing Music Cuts Dementia Risk 39%
November 24, 2025
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A MAJOR NEW STUDY suggests regularly listening to or playing music cuts dementia risk by up to 39%. Here’s the research — and how to use music to bring calm, connection, and cognitive support into everyday care.
Music Eases Sundowning, Lowers Dementia Risk
November 19, 2025
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A few minutes of music each day can calm sundowning and help support brain health. A new study explains these protective benefits — and we’ll show you how to build gentle musical routines into evening care.